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Filtered Search Results
Selleck Chemical LLC Methyl EudesMate S3863-25mg
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Methyl EudesMate (Methyl tri-O-methylgallate) is the methyl ester of 3 4 5-trimethoxybenzoic acid that used as an intermediate in the synthesis of pharmaceuticals
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Chem-Impex International, Inc. 1-Methylindole-3-carboxaldehyde | MFCD00014570 | 5G
1-Methylindole-3-carboxaldehyde, MFCD00014570, 5G
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Medchemexpress LLC Methyl 1H-indole-6-carboxylate | 50820-65-0 | MFCD00211063 | 98.3% | 175.19 g/mol | C10H9NO2 | 25 G
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Methyl 1H-indole-6-carboxylate is the methyl ester of 1H-indole-6-carboxylic acid used as an organic reagent and synthetic intermediate in medicinal chemistry and biochemical research. Supplied as a powder, it is suitable for use in synthesis, assay development, and as a building block in compound libraries.
- High purity suitable for research applications.
- Molecular formula C10H9NO2 and molecular weight 175.19 g/mol.
- Stable powder with recommended cold storage for long-term preservation.
- Available in multiple pack sizes for small-scale testing or bulk synthesis.
- Certificate of analysis and safety data sheet available.
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Ambeed 1Methyl1Hindole2carboxylic aci
1-Methyl-1H-indole-2-carboxylic acid, 16136-58-6, 98%
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Ambeed 1Methyl1Hindole2carboxylic aci
1-Methyl-1H-indole-2-carboxylic acid, 16136-58-6, 98%
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Medchemexpress LLC Farudodstat | 1035688-66-4 | 99.7% | 50 MG
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Farudodstat (ASLAN003) is an orally active and potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 35 nM for the human DHODH enzyme. It inhibits protein synthesis by activating AP-1 transcription factors. Farudodstat induces apoptosis and significantly prolongs survival in acute myeloid leukemia (AML) xenograft mice.
- Orally active and potent dihydroorotate dehydrogenase (DHODH) inhibitor
- Inhibits protein synthesis via activation of AP-1 transcription factors
- Induces apoptosis
- Substantially prolongs survival in acute myeloid leukemia (AML) xenograft mice
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eMolecules 100502-66-7 | Medchem Express | Abrucomstat | 5mg | 713706559 | HY-139566 | 121.092 | C3H7NO4
Pharmablock | isoxazole-4-boronic acid | 25mg | 629469772 | PBEB10426 | 1008139-25-0 | MFCD06657892 | 112.880 | C3H4BNO3
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eMolecules 914950-66-6 | Methyl 6-ethynylpicolinate | ChemScene | MFCD18207403 | 161.160 | C9H7NO2 | 98.000 | COC(=O)c1cccc(n1)C#C | 100mg | 717419550
Methyl 6-ethynylpicolinate | ChemScene | 914950-66-6 | MFCD18207403 | 161.160 | C9H7NO2 | 98.000 | COC(=O)c1cccc(n1)C#C | 100mg | 717419550
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Medchemexpress LLC Fatp1-in-2 | 2650944-83-3 | 98.8% | C19H20FN5O | 10MG
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FATP1-IN-2 is an arylpiperazine-derived small molecule research compound and an orally active inhibitor of fatty acid transport protein 1 (FATP1). It is used in preclinical studies to modulate fatty acid uptake and investigate FATP1-related metabolic processes.
- Orally active FATP1 inhibitor with reported potency in the low micromolar range.
- Human FATP1 IC50 = 0.43 μM; mouse FATP1 IC50 = 0.39 μM.
- High purity (~98.8%) suitable for research applications.
- Good solubility in DMSO (100 mg/mL); in vivo formulation protocols provided.
- Stable as a powder at -20°C with defined solvent storage conditions.
- Available in multiple pack sizes and as a prepared DMSO solution for convenience.
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Medchemexpress LLC Tryptamine | 61-54-1 | 98.0% | 160.22 | C10H12N2 | 10 MG
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Tryptamine (Standard) is an analytical reference standard of the endogenous monoamine tryptamine, supplied as a solid reference material for research and analytical applications. It is intended for identification and quantification in chromatographic and mass spectrometric methods, and for method development and quality control.
- Intended for analytical use as a reference standard for calibration and validation.
- Suitable for chromatographic and mass spectrometric identification and quantification.
- Offered in small laboratory pack sizes for convenient handling and storage.
- Accompanied by documented purity and a product datasheet for traceability.
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Medchemexpress LLC Sonolisib | 502632-66-8 | 5 MG
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Sonolisib (PX-866), an improved Wortmannin analogue, is an oral, irreversible, and pan-isoform inhibitor of PI3K. It inhibits the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and activation of the PI3K/Akt signaling pathway, which may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. It exhibits antitumor activity.
- Oral, irreversible, and pan-isoform inhibitor of PI3K
- Inhibits production of secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3)
- Inhibits activation of PI3K/Akt signaling pathway
- Exhibits antitumor activity
- May inhibit tumor cell growth and survival
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Medchemexpress LLC Oleoylcarnitine | 38677-66-6 | 99.95% | 425.64 | 1 MG
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Oleoylcarnitine is a metabolite that accumulates when fatty acid β-oxidation is suppressed. It can enhance hepatocarcinogenesis by activating STAT3.
- Enhances hepatocarcinogenesis via STAT3 activation.
- Accumulates in obesity-driven HCC tissues and serum of high-fat diet-fed mice.
- Increases in concentration in Dih10 cells with stable CPT2 knock down.
- Contributes to hepatocarcinogenesis by conferring stem cell properties to cancer cells.
- Purity: 99.95%.
- Appearance: Solid, white to off-white.
- Initial source: Endogenous metabolite.
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Medchemexpress LLC Tryptamine | 61-54-1 | MFCD00005661 | 99.9% | 5 G
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Tryptamine is a selective, blood-brain-penetrating 5-HT4 receptor agonist and an endogenous ligand of the aryl hydrocarbon receptor (AHR). It promotes intestinal anion secretion and fluid transport by activating G protein-coupled receptors (GPCRs) and accelerates gastrointestinal motility. Tryptamine can be used to study intestinal motility disorders such as functional constipation and has shown significant efficacy in multiple sclerosis models.
- Regulates Th17/Treg balance to inhibit neuroinflammation
- Competitively binds to 5-HT receptors to regulate central nervous system activity
- Participates in temperature regulation and spinal reflex regulation as a neuromodulator
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Medchemexpress LLC Quinocetone | 81810-66-4 | MFCD09753267 | 98.0% | 306.32 g/mol | C18H14N2O3 | 50MG
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Quinocetone is an antibacterial quinoxaline derivative supplied as an analytical standard for research and analytical testing. The compound is offered in solid and solution formats, and is characterized by a reported purity of 98.0%, chemical formula C18H14N2O3, and molecular weight 306.32 g/mol.
- Analytical standard suitable for method development and calibration.
- High purity for reliable quantitative results.
- Available in solid and solution formats for flexible use.
- Documented chemical identity with CAS 81810-66-4.
- Appropriate for laboratory research and reference analyses.
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Medchemexpress LLC Snt-207858 (free base) | 1104662-66-9 | 99.7% | 616.62 | 1 ML
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SNT-207858 free base is a selective, blood-brain barrier penetrating, potent, and orally active melanocortin-4 (MC-4) receptor antagonist. It demonstrates high affinity and selectivity for the MC-4 receptor, with an IC50 of 22 nM (binding) and 11 nM (function), showing 170-fold selectivity over MC-3 and 40-fold over MC-5. In preclinical studies, SNT-207858 significantly reduced tumor-induced weight loss in mice.
- Selective melanocortin-4 (MC-4) receptor antagonist
- Blood-brain barrier penetrating
- Orally active
- High potency with IC50 of 22 nM (binding) and 11 nM (function) on MC-4 receptor
- Shows 170-fold selectivity versus MC-3 and 40-fold selectivity versus MC-5
- Significantly reduces tumor-induced weight loss in mice with C26 adenocarcinoma-induced cachexia
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